ActiTide™ Bouncera na-anọchite anya ọganihu dị ukwuu na ihe ịchọ mma dabere na peptide, na-enye ngwọta dị mgbagwoju anya nke e mepụtara iji merie oke akụkọ ihe mere eme nke bioavailability peptide. Ọ bụ ezie na a maara peptides maka ikike mgbaàmà ha dị ndụ, ojiji ha na-abụkarị ihe mgbochi site na nnukwu hydrophilicity na nnukwu nha molekul, nke na-egbochi ikike ha ịbanye n'ime corneum stratum bara ụba na lipid. ActiTide™ Bouncera na-edozi ihe ịma aka ndị a site na ijikọta mgbagwoju anya triple-peptide synergistic na teknụzụ nnyefe dị egwu.
Imeri ihe mgbochi nnyefe site na iji teknụzụ Supramolecular
Usoro peptide ọdịnala na-enwekarị nsogbu nke ịmịkọrọ akpụkpọ ahụ nke ọma, nke na-eme ka ihe ndị na-arụ ọrụ na-anọgide n'elu akpụkpọ ahụ na-erughi akwa akpụkpọ ahụ achọrọ. ActiTide™ Bouncera na-edozi nke a site na iji Supramolecular Synergistic Penetration Technology, nke nwere mmiri mmiri DES-TG supramolecular ionic.
Usoro ọhụrụ a na-emepụta usoro nnyefe a haziri ahazi ebe a na-ahazi peptides—Palmitoyl Tripeptide-5, Hexapeptide-9, na Hexapeptide-11—n'ime ihe dị n'ime supramolecular complex. Teknụzụ a na-agbanwe ikike mgbochi akpụkpọ ahụ n'ụzọ a na-achịkwa ma "na-anabata nhazi", na-ahụ na ihe ndị na-arụ ọrụ na-abanye nke ọma n'ime epidermis na dermis miri emi n'emebighị ịdị ọcha nke akpụkpọ ahụ.
Ntinye aka na nnweta bioavailability akwadoro
A na-egosi na nkà na ụzụ ActiTide™ Bouncera dị elu site na nnyocha siri ike nke in vitro. Site na iji teknụzụ fluorescence tracer dị elu, a tụlere njirimara injection nke peptides nke ọ bụla n'ime mgbagwoju anya ahụ. Ọmụmụ ihe ahụ gosiri na ActiTide™ Bouncera na-enweta ike injection nke dị okpukpu atọ ruo ise karịa nke otu njikwa maka peptide nke ọ bụla. Foto fluorescence kwadoro nleba anya miri emi nke akpụkpọ ahụ, na-ahụ na ihe ndị na-arụ ọrụ biopeptide ruru fibroblasts na Dermal-Epidermal Junction (DEJ) ebe ha nwere ike inwe mmetụta kachasị.
Ọrụ Dị Iche Iche na Ịrụgharị Akpụkpọ Ahụ
Karịa nnyefe ya dị elu, ActiTide™ Bouncera na-egosipụta nnukwu ọrụ bioactivity n'ọtụtụ ụzọ ịka nká na ọmụmụ nnwale:
Nkwado Nhazi DEJ: Ọ na-eme ka mmepụta mkpụrụ ndụ ihe nketa nke Collagen IV na VII dịkwuo elu nke ukwuu, protein dị mkpa maka ime ka njikọ Dermal-Epidermal sikwuo ike ma weghachite nkwado ntọala nke akpụkpọ ahụ.
Njikọta Collagen: Na nnwale arụmọrụ, mkpokọta nke naanị 0.15% kwalitere njikọta Collagen Type I site na 332.32%, na-egosi ikike dị ike maka ịbawanye matriks akpụkpọ ahụ na ibelata omimi wrinkles.
Mgbochi nke mmebi collagen na mfu collagen: Ọ na-enye nchebe siri ike site na igbochi MMP-1 (enzyme nke na-akpata mmebi collagen). Na mkpokọta 0.10%, ọkwa MMP-1 belatara site na 94.66%, nke na-arụ ọrụ karịa Vitamin C na arụmọrụ tụnyere.
Njirimara na Ngwa Physicochemical
N'ihe gbasara ahụike, ActiTide™ Bouncera bụ mmiri mmiri na-enweghị agba na-apụta ìhè, nke e mere maka nkwụsi ike kacha mma na ịdị mfe nke nhazi. Ọ dabara nke ọma na ọtụtụ ngwaahịa nlekọta akpụkpọ ahụ dị elu, gụnyere serum dị elu, ude na-eme ka ọ sie ike, na ihe mkpuchi ihu na-emegharị ahụ. Usoro akwadoro nke 0.2–5.0% na-enye ohere maka ojiji dị iche iche na usoro ndị na-elekwasị anya na mbelata mkpụkọ miri emi na ime ka akpụkpọ ahụ dịghachi ọhụrụ.
Na nchịkọta, ActiTide™ Bouncera nwere nnukwu mmụba teknụzụ site na iji peptide nkịtị ruo na nnyefe teknụzụ bayotechnological dị elu. Site na ijikọta nkenke nke mgbagwoju anya triple-peptide na ike nke Supramolecular Synergistic Penetration, ọ na-enye ngwọta dị elu na arụmọrụ dị elu maka ọgbọ na-esote nke nlekọta akpụkpọ ahụ ọkachamara. O gosipụtara nchekwa, ikike ịbanye n'ime miri emi (na-eru ihe karịrị ugboro 3-5 nke njikwa ọkọlọtọ), yana arụmọrụ dị egwu na-etinye ya dị ka ihe dị mkpa maka ụdị ịchọ mma zuru ụwa ọnụ na-achọ nsonaazụ sayensị akwadoro.
Oge ozi: Jenụwarị-07-2026