Otu Teknụzụ Recombinant si akọwapụta PDRN ọzọ

Ruo ọtụtụ iri afọ, PDRN adaberewo na mwepụta sitere na mkpụrụ ndụ ọmụmụ salmon. Ụzọ ọdịnala a na-egbochi site na mgbanwe dị na ọkọnọ azụ, usoro DNA na-enweghị usoro, na ihe ịma aka na njikwa ịdị ọcha - na-eme ka nguzosi ike ogologo oge, nhazi, na nrubeisi iwu sie ike ikwenye.

Nke anyịPDRN ndị na-emegharị ihee mepụtara iji merie ihe mgbochi nhazi ndị a site na injinia bio dị elu.

Enweghị ihe sitere na anụmanụ, e wuru ya na biosynthesis a na-achịkwa
Site na iji E. coli DH5α dị ka ikpo okwu mmepụta ihe dị ndụ, a na-ewebata usoro PDRN kpọmkwem site na vektọ recombinant ma na-emegharị ha nke ọma site na ịgbakọ nje bacteria.
Ụzọ a na-ewepụ ịdabere na ihe ndị sitere na azụ, na-edozi nsogbu nchekwa nke ọkọnọ na nchekwa anụmanụ n'ebe a na-esi enweta ya, ebe ọ na-ekwekọ na ụkpụrụ iwu kachasị sie ike na EU, US, na ahịa ụwa.
N'otu oge ahụ, ngwaahịa ahụ ka na-anọgideDabere na DNA ma bụrụ nke e si n'okike mepụta, na-eme ka ọ bụrụihe ọzọ dị ka vegan, nke na-abụghị anụmanụ, mana ọ bụ ihe ọzọ dị adị n'ihe gbasara ndụgaa na PDRN nke sitere na azụ salmon ọdịnala.

Usoro ndị e mere nke ọma, ọ bụghị mwepụta na-enweghị usoro
N'adịghị ka PDRN nkịtị nke a na-enweta site na mmịpụta na-abụghị nke nhọrọ, teknụzụ recombinant na-enye oherenjikwa zuru oke na usoro DNA na ogologo iberibe.

Enwere ike ịhazi usoro mkpụmkpụ maka ojiji mgbochi mkpali

Enwere ike ịhazi usoro nhazi nke dị n'etiti ruo ogologo iji kwado mmeghari collagen na ndozi akpụkpọ ahụ

Mgbanwe a—site na mwepụta enweghị usoro gaa na biosynthesis ezubere iche—na-emepe ohere ọhụrụ maka mmepe nke ọrụ na usoro ahaziri ahazi.

Nhazi na mmepụta ihe nke ọkwa ụlọ ọrụ mmepụta ihe
Site na ijikọta mgbanwe okpomọkụ-ujo kachasị mma na nkwadebe mkpụrụ ndụ nwere oke arụmọrụ dị elu, nnabata plasmid na mmepụta mmepụta na-akawanye mma nke ukwuu.
N'ịjikọta ya na ịkpụcha anụ ahụ nke nwere ọtụtụ nzọụkwụ na nhicha chromatographic enyere iwu, usoro ahụ na-arụ ọrụ mgbe niileỊdị ọcha nke ọkwa biomedical (≥99.5%).
Usoro ịgbaze agbazi nke a haziri ahazi na-eme ka mmụba dị mma site na mmepụta nnwale ruo na mmepụta azụmaahịa.

A kwadoro arụmọrụ nke data tupu ọgwụgwọ
Ọmụmụ ihe tupu oge ahụike na-egosi na PDRN recombinant na-enyemkpali dị elu nke njikọ collagen nke ụdị mmadụ nke mbụma e jiri ya tụnyere PDRN na DNA-metal complexes sitere na salmon.
Nsonaazụ ndị a na-akwado ojiji ya na ndozi akpụkpọ ahụ na mgbochi ịka nká, na-enyengwọta ihe eji eme ihe nke a na-achọpụta site na data, nke usoro ya na-achịkwa.

PDRN nke na-agbanwe agbanwe karịrị ihe nnọchi anya ya—ọ bụ nkwalite teknụzụ.
Site na ijikọta nhazi usoro ziri ezi na biosynthesis a na-achịkwa, teknụzụ recombinant na-eme ka ọrụ PDRN dịkwuo elu ebe ọ na-enyekwụsiri ike, vegan, na ihe ọzọ sitere n'okikegaa na PDRN sitere na anụmanụ—na-edobe ihe atụ ọhụrụ maka ihe ndị na-eme ka akpụkpọ ahụ dịghachi ọhụrụ.