Aha ahia | UniAPI-PBS |
CAS | 1405-20-5 |
Aha ngwaahịa | Polymyxin B sulfate |
Ọdịdị | Na-acha ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ntụ ntụ |
Solubility | Mmiri soluble |
Ngwa | Ọgwụ |
Nyocha | Nchikota nke polymyxin B1, B2, B3 na B1-I: 80.0% minPolymyxin B3: 6.0% maxPolymyxin B1-I: 15.0% max |
ngwugwu | 1kg net kwa aluminum nwere ike |
Ndụ nchekwa | afọ 2 |
Nchekwa | Chekwaa n'ebe dị jụụ na nke kpọrọ nkụ, pụọ na ìhè. 2 ~ 8 ℃ maka nchekwa. |
Ọdịdị Chemical |
Ngwa
Polyxin B sulfate bụ ọgwụ nje cationic surfactant, ngwakọta nke polyxin B1 na B2, nke nwere ike melite permeability nke akpụkpọ ahụ cell. Ọ fọrọ nke nta ka enweghị isi. Na-enwe mmetụta maka ọkụ. Hygroscopic. Soluble na mmiri, ntakịrị soluble na ethanol.
Mmetụta ụlọ ọgwụ
Ụdị nje bacteria ya na ngwa ụlọ ọgwụ yiri polymyxin e. ọ nwere mmetụta mgbochi ma ọ bụ nje bacteria na nje gram-adịghị mma, dị ka Escherichia coli, Pseudomonas aeruginosa, paraescherichia coli, Klebsiella pneumoniae, acidophilus, pertussis na ọnyụnyụ ọbara. N'ụlọ ọgwụ, a na-ejikarị ya maka ọrịa nke nje bacteria na-emetụ n'ahụ, ọrịa urinary system nke Pseudomonas aeruginosa kpatara, anya, trachea, meningitis, sepsis, ọrịa ọkụ, akpụkpọ anụ na akpụkpọ anụ mucous, wdg.
pharmacological omume
Ọ nwere mmetụta antibacterial na Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus, enterobacter, Salmonella, Shigella, pertussis, pasteurella na Vibrio. Proteus, Neisseria, Serratia, pruvidens, gram-positive bacteria na anaerobes na-ahụ maka ọgwụ ndị a anaghị emetụ n'ahụ. Enwere mgbochi n'etiti ọgwụ a na polymyxin E, mana enweghị mgbochi n'etiti ọgwụ a na ọgwụ nje ndị ọzọ.
A na-ejikarị ya maka ọnya, eriri afọ, anya, ntị, ọrịa trachea nke Pseudomonas aeruginosa na ndị ọzọ Pseudomonas kpatara. Enwere ike iji ya maka sepsis na peritonitis.